淋巴造血統(tǒng)結(jié)構(gòu)ppt課件

1、diseases of lymphoid and hematopoietictissues / system淋巴造血組織系統(tǒng)疾病淋巴造血組織系統(tǒng)疾病淋巴網(wǎng)狀組織：結(jié)構(gòu)和功能淋巴網(wǎng)狀組織：結(jié)構(gòu)和功能天津醫(yī)科大學(xué) 病理學(xué)教研室器器 官官 lymphomaall over the body 周身淋巴組織的分布transformation of lymphocytes淋巴細(xì)胞轉(zhuǎn)化淋巴細(xì)胞轉(zhuǎn)化淋巴細(xì)胞轉(zhuǎn)化：b細(xì)胞培養(yǎng)中的淋巴細(xì)胞，培養(yǎng)中的淋巴細(xì)胞，受植物血凝素作用后：受植物血凝素作用后：a.0a.0小時小時b.1b.1小時小時c-f.24c-f.24小時小時淋巴細(xì)胞轉(zhuǎn)化依lennert(1975)淋巴細(xì)

2、胞系：一些細(xì)胞類型的光鏡形態(tài)mucosa-associated lymphoid tissues(malt)黏膜相關(guān)淋巴組織黏膜相關(guān)淋巴組織黏膜相關(guān)淋巴組織fcmzmar黏膜相關(guān)淋巴組織淋巴瘤黏膜相關(guān)淋巴組織淋巴瘤maltoma胃maltoma ：淋巴上皮病變?nèi)賛altoma ：淋巴上皮病變?nèi)橄賛altoma ：淋巴上皮病變子宮內(nèi)膜maltoma：淋巴上皮病變1. fibrous frame纖維性網(wǎng)架igm, ig, iga or ige, igd)(igm),igm+lymphoid parenchyma 淋巴組織實質(zhì)the evolution of follicles 淋巴濾泡的演化di

3、rection of antigen influxmantle zone thicker at the top (corona)light zone of germinal centerdark zone of germinal center (more large cells)light zonedark zonestary skystary skycentrocytescentroblaststingible body cellsfdcfdccd21(fdc)中心母細(xì)胞中心細(xì)胞漿母細(xì)胞cd20(b cdlls)cd45ro(t cells)marginal zone cells (igm)

4、mantle zone cells (igm+d)follicle center cells (igm, igg, iga or ige, not igd)mentle zone/mentle cells淋巴濾泡：套層/套細(xì)胞marginal zone / marginal cells (monocytoid b cells)淋巴濾泡：邊緣區(qū)/邊緣區(qū)細(xì)胞 (單核細(xì)胞樣b細(xì)胞)*macmcas macmcas mantle zonemantle cellsmantle zonemarginal zoneparacortexparacortexidcparacortexcd3cd20sinus histiocytesmedul